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EDUCATION

Sep.2018 – Jul.2024
Ph.D. in Biology
School of Life Sciences and Technology, Tongji University, China

Sep.2014 – Jun.2018
B.S. in Biotechnology
School of Life Sciences, Shandong Normal University, China

Sep. 2025 – Present
Research Scientist
Sycamore Research Institute of Life Sciences, Shanghai

Jul.2024 – Sep.2025
Research assistant
School of Life Sciences, Shandong Normal University, China

Developed and applied computational methods to analyze single-cell and spatial data
- Developed SCRIP (Single-Cell Gene Regulation Inference using ChIP-seq), a method integrating scATAC-seq and bulk TR ChIP-seq to infer single-cell TR activity and targets. SCRIP outperformed motif-based approaches in TR binding activity assessment and enabled identification of TR target genes and construction of single-cell gene regulation networks. With the advances of single-cell multiomics techniques, we updated it to SCRIPro, which suits both single-cell and spatial multiomics data.
- Developed TISCH (Tumor Immune Single Cell Hub) and TISCH2, a curated resource integrating single-cell transcriptome profiles from ~6 million cells across 50 cancer types, enabling systematic comparison of gene expression and immune system heterogeneity to inform immunotherapy research.
Large-scale genomic data mining and integration analysis
- Developed CHIPS, a pipeline that processes epigenome data into readable results with a single command. CHIPS integrates state-of-the-art tools for cistrome NGS data and automates parameter selection.
- Developed and maintained the Cistrome Data Browser, which hosts many public cistrome sequence datasets, offering a user-friendly interface to access the data quality and the results of downstream analysis.

2024
- Poster Speaking, Human Cell Atlas Asia 2024, Hong Kong SAR, China
- Poster Speaking, The 2nd Yangtze River Delta Bioinformatics Conference, Shanghai, China
2023
- Poster Speaking, Systems Biology of Gene Regulation and Genome Editing, Cold Spring Harbor Conferences Asia, Suzhou, China
- Poster Speaking, The WLA Research Conference on Cells and Genes, Shanghai, China
- Poster Speaking, 11st National Conference on Bioinformatics and Systems Biology, Guangzhou, China
2021
- Poster Speaking, Human Cell Atlas Asia 2021 Meeting, Online
- Poster Speaking, 10th National Conference on Bioinformatics and Systems Biology, Chengdu, China